You might think that Alzheimer’s is something that only affects your friend̵7;s grandfather. But we are learning that cognitive decline is alarmingly common. in fact Alzheimer’s Association experts estimate that 12 to 18 percent of Americans age 60 and older experience some form of mild cognitive impairment (MCI), which often progresses to a highly diagnoseable form. It’s official of dementia. including Alzheimer’s disease
This week, the U.S. Food and Drug Administration (FDA) has expedited action on aducanamab, the first drug that may slow the progression of early diagnosed Alzheimer’s disease. But there isn’t a cure for any form of dementia yet, so our best bet is to do everything we can to prevent it in the first place. We recently learned that walking three times a week plays a role. Music and Mediterranean diets can help keep your brain healthy as you age.
New research published June 1 in Biology PLOS Add one more brain-healthy tip to your Alzheimer’s prevention arsenal: deep sleep.
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Scientists at Pennsylvania State University discovered that sleep-dependent brain activity that occurs during deep sleep and restless sleep (NREM) helps the body excrete toxic proteins associated with Alzheimer’s disease. MER (ICYMI, we’ve just learned that a healthy gut can help you sleep better and more quality. So be sure to load up your diet with probiotics, prebiotics, and fermented foods!)
Extensive research suggests that Alzheimer’s disease occurs when levels of the protein amyloid-β (Aβ) and tau build up in the brain. This usually occurs 10 to 20 years before the official diagnosis. However, this is not the first study to indicate protein burden on the brain and its link to sleep: In 2018, scientists found that nighttime sleep deprivation A single would increase the Aβ load within the brain.
Cerebrospinal fluid (CSF) can excrete these waste products from the body through the lymphatic system, which is part of the central nervous system. Glial cells in the brain work with blood vessels to help protect nerve cells from physical and chemical damage. If the lymphatic system cannot drain This “waste in the brain” effectively. The buildup of these extracellular proteins could progress to Alzheimer’s disease.
But deep sleep may help the brain flush out these Alzheimer’s-related toxins. During sleep, NREM, which is a characteristic that occurs when *really difficult to wake up* because you’re “not fully”, the brain generates slow, steady electrical pulses that act as an internal cleansing mechanism.
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“Study links coupling between global brain activity in resting states and [CSF] flows to Alzheimer’s disease These findings underscore the possible role of low frequencies (less than 0.1 [hertz]) Resting state of neurological and physiological changes in degenerative diseases of the nervous system. Probably because of the sleep drive of [CSF] flow to detoxify the brain,” says Xiao Liu, Ph.D., an assistant professor of biomedical engineering at Pennsylvania State University. medical news today.
The study authors caution that this is not a proven situation (yet), but recommend adding sleep analysis to the Alzheimer’s disease detection protocol.
Regardless of scheduling, getting enough sleep (AKA seven to nine hours) certainly doesn’t sound like a bad prescription! In case you can use R&R rehab, we spoke with sleep experts to outline 4 ways to sleep better.