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Gut bacteria linked to disease severity, immune response High mental health found in the ICU

By Nancy Lapid

(Reuters) – The following is a summary of the latest scientific studies on the novel coronavirus and efforts to find a cure and vaccine for COVID-19, a viral illness.

Gut bacteria linked to virulence of COVID-19 immune response

The microscopic organisms that live in our gut can influence the severity of COVID-19 and the body’s immune response, and may cause persistent symptoms, researchers report Monday in the journal Gut. They found that the gut microbes in COVID-19 patients are very different from those in non-infected people. “COVID patients are deficient in certain good bacteria known to regulate our immune system,”

; said Dr. Siew Ng. The presence of abnormal gut bacteria, or “dysbiosis”, persists after the virus has been depleted and may play a role in the prolonged symptoms that plague the epidemic, according to The Chinese University of Hong Kong. In some patients Her team developed an oral formula of live bacteria called probiotics and a special capsule to protect the organism until it reaches the gut. “Compared to patients receiving standard care, our pilot clinical studies show that more COVID patients receiving our microbiome immune formulation are able to resolve symptoms completely,” Ng said. He added that people who received the drug had a significant decrease in the blood-inflammatory markers. Bacteria in the feces and develop antibodies to the virus neutralize (https://bit.ly/3q9u1hb)

The epidemic affected the mental health of the ICU workers.

Nearly half of the workforce in the intensive care unit (ICU) in England experienced severe anxiety, depression or post-traumatic stress disorder, feeling they were likely to improve upon their death, researchers reported Wednesday. In the field of occupational medicine The study was conducted in June and July, before Britain began to experience the latest in hospitalizations. Among more than 700 healthcare workers in 9 ICU, 45% met the criteria for the potential clinical significance for at least one of four serious mental health disorders: severe depression. (6%), PTSD (40%), severe anxiety (11%), or drinking problems (7%), more than one in eight reported self-harming or suicidal thoughts more often in the second. Last week The researchers said the poor mental health among ICU staff caring for the seriously ill and fatal COVID-19 patients was not just the worst. But adversely affect the quality of life But also reduced the ability to work effectively. The findings highlight the urgent need for mental health services to be immediately accessible to all healthcare professionals. (https://bit.ly/2LN5SOQ; https://reut.rs/38GlzAn)

Cooling Vest Nursing Aid COVID-19 Resistant to PPE

Nurses in COVID-19 wards wearing cooling vests under personal protective equipment (PPE) felt less heat load during shift work. Seventeen-year-old nurses wore lightweight cooling vests under their PPE one day and the PPE only on the other. On both days, the participants swallowed an electronic capsule, which provided continuous core body temperature readings. Such a shirt leads to a slight improvement in body temperature. But feeling overheated, researchers report in the journal Temperature, only 18% of nurses reported feeling uncomfortable and 35% feeling slightly hot at the end of the day with a vest, compared to 81% and 94%, respectively, today. “PPE is known to induce heat stress, which increases fatigue and sensory dissatisfaction, and is known to influence effective decision-making,” said study co-author Thijs. According to Eijsvogels, from Radboud University Medical Center in the Netherlands, CoolOver coats, made by Dutch company Inuteq, are easy to sterilize and reactivate in refrigerators, he said, and may extend their tolerance times and improve recovery. Physicians involved in COVID-19 care (https://bit.ly/2K9sXe5)

Diabetes increases the risk of COVID-19 for black patients.

Black patients with type 1 diabetes mellitus (T1D) infected with the novel coronavirus are at particularly high risk of a life-threatening diabetes complication called T1D ketoacidosis. In children or adults and need daily insulin to survive The researchers studied 180 patients from across the United States with T1D and COVID-19, including 31% who were blacks and 26% who were Hispanic. Black patients were nearly four times more likely to develop diabetes ketocidosis (DKA) compared to white patients, researchers report in The Journal of Clinical Endocrinology and Metabolism.Hispanic people were at a higher risk than skin patients. Slightly white Blacks and Hispanic descent were less likely to use new diabetes technologies, such as continuous glucose monitoring and insulin pumps, and had significantly worse blood sugar control compared to white patients. That suggests that higher risks are likely the result of structural and systemic inequality. Especially during a pandemic, healthcare providers need to screen patients with T1D for socioeconomic factors that increase the risk of DKA, such as food insecurity, affordability. Insulin and access to diabetes devices (http://bit.ly/3hWJZs8)

Open https://tmsnrt.rs/3a5EyDh. In an external browser to view a Reuters graphic on developing vaccines and treatments.

(Reporting by Nancy Lapid and Megan Brooks; Edited by Bill Berkrot)

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