Like the coronavirus itself, the vaccine against COVID-19 can affect everyone differently. Some of them have no side effects. Some people stay in bed for a few days. And while some people build strong immunity after they’ve been vaccinated. But some people are not so lucky. Although it’s hard to predict how you’ll react. Medical experts have warned that people with autoimmune diseases or those who take immunosuppressants may not have a strong response, and now a new study finds that a certain group of people are more likely to have a lower immune system, especially after taking immunosuppressants. get vaccinated. In fact, half of them have not antibodies after vaccination
The May study published in Journal of the American Medical Association It found that 46 percent of transplant patients who received two doses of Moderna or Pfizer vaccine did not produce antibodies to COVID-19, a key indicator of whether the vaccine was effective. The good news is that another 40 percent of the 658 transplant patients studied had no antibodies after the first vaccination. But antibodies developed after the second shot. However, many patients remain unprotected against COVID.
“This is a more stark difference than we expected.” Dorri SegevDr. Johns Hopkins Hospital, a transplant surgeon, told CBS News, “I’ve heard that transplants and other immunocompromised patients are getting better. vaccinated and relaxed safety behaviors and is now being hospitalized. and some have died from contracting COVID-19.”
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in the same way April research from the Mayo Clinic, published in American Journal of TransplantationIt has also raised concerns that transplant patients appear to have a weakened immune response to the COVID-19 vaccine. A small study looked at seven organ transplant recipients diagnosed with COVID-19 at the Mayo Clinic in Florida. After receiving either the mRNA vaccine from Pfizer or Moderna, two patients received one dose. S and five were fully vaccinated. Five were hospitalized, with three requiring oxygen after discharge. Only one patient had anti-COVID antibodies. The research team therefore estimates that infection rates in vaccinated solid organ transplant recipients are 10 times higher than the general population.
“This study is eye-opening for the transplant community,” lead researcher. Hani WadeiMD, a nephrologist at the Mayo Clinic Transplant Center, said in a statement. “Our study suggests that transplant patients do not have the same immune response as the general population. They became infected after receiving the vaccine and canceled preventive measures. thinking that they are immune to the virus.”
Wadei added: “Care should be given to patients vaccinated against solid organ transplant immunosuppression until we have a better vaccine strategy … all individuals, especially patients receiving Implants should follow preventive measures such as social distancing, wearing masks and regular hand hygiene.”
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Another study published earlier this month in the journal annals of rheumatism, Consider the two cohorts vaccinated against COVID-19: 84 patients with autoimmune diseases (eg rheumatoid arthritis, rheumatoid arthritis). inflammatory bowel disease), psoriasis and some arthritis) and 182 healthy participants. In the latter group, all but one patient developed anti-COVID-19 antibodies in the past. Up to 1 in 10 people failed to develop antibodies.
especially Research has shown that patients taking methotrexate (sold as Rheumatrex, Trexall, Otrexup, Rasuvo) and rituximab (Rituxan) for their autoimmune diseases respond poorly to vaccines, WebMD reports. suppress the immune system Therefore, disorders that cause your immune system to become overactive will be controlled.
Like Wadei, the Centers for Disease and Prevention (CDC) has warned people with impaired immune systems. including those who have received an organ transplant You should continue to wear the mask even after you have been fully vaccinated. “If you have a medical condition or are taking medication that weakens your immune system. You may not be fully protected even if you are fully vaccinated,” read the CDC’s guidelines, updated in mid-May. “Even after vaccination You may continue to take all precautions.”
Director of CDC Rochelle Walensky, MD, expanded on that advice during an appearance on NBC’s meet the press On May 16th, “We know—and there’s new information to suggest—that if you don’t have a fully capable immune system from chemotherapy, from implants, from other immunomodulators, you’re going to have to do it.” that the vaccine might not work as good for you,” she said. should consult a doctor.”
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