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‘Microbiome’ may affect COVID-19 severity



WEDNESDAY, Jan. 13, 2021 (HealthDay News) – The bacteria in your gut may play a role in the severity of COVID-19 infection and the strength of your immune response.

Not only that, an imbalance in the microbiome can cause ongoing inflammation, often referred to as “distant” COVID.

“The imbalance in the microbiome contributes to the severity of COVID-19 and, if persisted after viral eradication, could result in ongoing symptoms and multiple systemic inflammatory syndromes such as prolonged COVID syndrome. Institute of Gastroenterology of the Chinese University of Hong Kong

“Restoring the missing beneficial bacteria may improve our immunity to SARS-COVI-2 and speed up recovery from disease,”

; she said. “COVID-19 management should not be aimed solely at virus elimination. But still need to restore the intestinal microflora as well “

However, the study cannot prove that imbalances in the microbiome only aggravate COVID-19. But there appears to be a relationship between viruses and bacteria in the gut, Ng said.

But there is growing evidence that bacteria in the gut are linked to inflammatory disease.

For the study, the researchers studied blood and feces samples from 100 patients with COVID-19 and 78 without infection as part of the microbiome study before the outbreak began.

They found that in 274 stool samples of the gut microbiome, there was a significant difference between patients with and without COVID-19, whether they were taking the drug or not, including antibiotics.

For example, people with COVID-19 have fewer bacteria that may affect the immune response than those without the infection. Decreased bacterial counts are linked to the severity of infection.

The researchers found that the number of these bacteria remained low for up to 30 days after the infected patients had cleared the virus.

COVID-19 stimulates the immune system to produce inflammatory cytokines, and in some cases, this response can be excessive, causing extensive tissue damage, shock, and organ failure.

Analysis of blood samples revealed that microbial imbalances in COVID-19 patients were linked to high levels of inflammatory cytokines and indicators of blood tissue damage such as C-reactive protein.




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