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Most children with MIS-C have very few symptoms of the coronavirus before they develop inflammation.



Most children with rare systemic inflammatory disease But serious in children (MIS-C) that occurred several weeks after coronavirus infection had little or no symptoms of COVID-19, or only very few symptoms. Analysis of such cases in children is the largest in the United States.

The study, led by researchers at the Centers for Disease Control and Prevention (CDC) and published Tuesday in the medical journal JAMA Pediatrics, examined nearly 1,800 MIS-C cases reported to the CDC between March 2020 and mid-month. January of this year, the study included children up to 20, although most were younger than 15.

MIS-C is a condition that often causes parts of the body to become inflamed, including the heart, lungs, kidneys, brain, skin, eyes, or digestive organs, according to the CDC, which on its website shows it has been reported by states to date. March 29, a total of 3,1

85 cases and 36 deaths, MIS-C may be mistaken for Kawasaki disease, a rare condition that can cause red, swollen skin and heart problems. But the two are not the same Most children with MIS-C recover, although some may require hospitalization.

The study authors found that most of the patients studied – approximately 75% – did not experience symptoms of COVID-19 when they were infected with coronavirus. However, when patients develop MIS-C later, usually two to five weeks later, fever is the most common symptom, the CDC analysis found.

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Abdominal pain, vomiting, diarrhea, and skin redness occurred in at least half of the affected children, while almost a third had heart attacks or other heart involvement. Children up to 4 years of age are less likely to need intensive care than older children.

The CDC, in the study, said their findings add to the existing theory that MIS-C is likely a delayed immune response to COVID-19 infection.

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“In a cross-sectional study of a large cohort of patients with MIS-C, two peaks following the peak of COVID-19 were observed within 2 to 5 weeks. The geographic and transient relationships of MIS- C with the COVID-19 outbreak suggests that MIS-C is the result of a delayed immune response to SARS-CoV-2 infection.Clinical symptoms vary with age and presence or absence. Was before COVID-19 “according to the study.

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MIS-C treatments often include steroids to reduce inflammation. Although the symptoms made some children seriously ill, such as one Michigan boy, had four amputations of arms and legs after developing MIS-C, most of the developed children recovered fully.

Experts emphasize that the coronavirus vaccine is the best way to prevent COVID-19 infection with the ongoing study of the COVID-19 vaccine in children. For example, Pfizer and Biotech announced late last month that Phase III trials on the coronavirus vaccine in adolescents aged 12 to 15 were found to be 100% safe and effective.

“The clinical manifestations of patients with MIS-C varied with age and the previous presence or absence of COVID-19, the development of laboratory markers or diagnostic methods to differentiate MIS-C from clinical trials. Severe COVID-19 illness and over-inflammatory conditions, such as Kawasaki disease. It is critical to early and timely diagnosis and treatment. “The authors of the study concluded partially. “As the COVID-19 epidemic spreads to the third highest and is becoming more common across the United States, doctors should maintain a high index of MIS-C suspicion to diagnose and treat it. Immediately, practitioners should report suspected MIS-C patients to local and state health authorities. “

Fox News’ Kayla Rivas and Associated Press contributed to this report.


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