A research study involving 90 participants indicated that MDMA, commonly known as ecstasy or molly, when paired with talk therapy, can help people suffering from post-traumatic stress disorder (PTSD). The York Times reports. On monday
The study, which was obtained from the Times and not yet published, indicated that two months after treatment, 67 percent of participants who received MDMA were no longer qualified for a PTSD diagnosis, compared with 32 percent who did not. Medicines.
The research is expected to be published in Nature Medicine later this month and brings MDMA one step closer to receiving approval from the Food and Drug Administration (FDA) for therapeutic use. The FDA will have to re-analyze the third phase of trials showing the benefits of MDMA therapy for PTSD, with the earliest approval in 2023.
The Times noted that MDMA received without treatment did not necessarily result in any improvement in PTSD symptoms.
“It̵7;s not a drug, it’s a drug-enhanced therapy,” Rick Doblin, the study’s senior author and director of interdisciplinary psychedelic studies, told the Times.
The study found no serious side effects in participants with MDMA, with mild side effects including nausea and loss of appetite.
Prior to taking MDMA or a placebo, the participants had a first meeting with two trained therapists. They then underwent eight-hour therapy three times a month, during which they were given either a pill or a placebo.
The participants and their therapists were unaware of whether the participants received either MDMA or a placebo.Most participants were able to accurately predict what they had received. But this does not destroy results or methods.
Eighty therapists from 15 sites in the United States, Canada, and Israel gathered data on 90 participants, each having severe PTSD symptoms and were previously diagnosed, on average for more than 14 years. This includes combat veterans, first responders and victims of rape, mass shootings, domestic violence or childhood injuries.
“This is as exciting as I can get about clinical trials,” Gul Dolen, a neuroscientist at the Johns Hopkins University School of Medicine who was not involved in the study, told the Times. This is in the results of a clinical trial for psychiatric neurosis. “
MDMA became known as ecstasy when it began to be used on dance floors rather than by therapists in the early 1980s, causing crime. Unlike MDMA, ecstasy or molly may include other risky substances and may be given in higher, more unsafe doses.
Mental health experts told the Times that the study could lead to more studies on MDMA’s ability to treat other mental disorders and its ability to heal other hallucinogenic disorders, but others urged. Careful after the study included Allen James Frances, professor emeritus and former chair of psychiatry at Duke University.
“All new therapies in medicine often have a temporary effect on the basis of newness and promise more than is possible,” Frances told the newspaper.