Syracuse, NY – An 8-month-old baby from Baldwinsville. It is the youngest person in the world to receive two doses of the Pfizer Covid-19 vaccine.
Vincenzo “Enzo” Mincolla received a second dose Wednesday at Upstate Medical University, where he is participating in clinical trials.
The North is only one of four in the United States, the only place in the world to test the Pfizer vaccine in children under five.So far, the federal government has only approved the vaccine for children as young as 12.
Enzo was one of 16 of the four infants who took part in Phase 1 of the trial, including children aged 6 months to 2 years.
Enzo, who was first shot three weeks ago when he was 7 months old, was the youngest, according to Dr. Joseph Domashowske, a pediatric infectious disease physician in upstate, and the trial’s lead investigator. Five more infants were included in the state trial.
Enzo Mike and Marissa Mincolla’s parents are doctors.
“We both feel that ending this epidemic is important, and the fastest and safest way is to get vaccinated for a solution,” said Mike Mincolla.
Mike Mincolla is a family medicine physician at CNY Family Care in East Syracuse.Marissa Mincolla is a radiologist at Upstate.
They had no certainty about getting the baby vaccine, Mike Mincolla said.After he took the picture, Enzo was sleeping and eating well, frustratingly, and experiencing no side effects.
Mincolla said he frequently encountered patients who were reluctant to get the Covid-19 vaccine.
“I told them that ‘I am very comfortable with this vaccine for my 7-month-old,’ he said. “It is safe, effective and effective.”
Mincolla said his son’s involvement in the trial is part of history. “We are helping science and evidence-based medicine,” he said.
The Mincollas also have a 4-year-old daughter they signed up for in the Second Phase of the Northern Tribunal.
Enzo and the other infants received two 3 mcg vaccines three weeks apart. That is one-tenth of the number of vaccines that adults receive.
Pfizer has temporarily halted trials to determine if the baby was receiving the correct medication, Domashowske said.
“The concern is that the dose may be too low for that age group,” he said, because all babies are well tolerated of the vaccine without any side effects.
A blood test is being done to determine if an immunized infant has developed antibodies to fight COVID-19.If the blood test shows that the baby has low or no antibody levels, Pfizer may decide to test 16 other babies at higher doses, for example: 10 micrograms, he said.
Covid-19 cases are usually mild in children. But some children with Covid-19 will develop Pediatric Multisystem Inflammatory Syndrome, or MIS-C.This is a serious condition that can cause severe inflammation of the heart, lungs, blood vessels, kidneys, digestive system, brain, skin, or eyes. Northern has cared for more than 100 children with MIS-C since the outbreak began, Domashowske said.
“In general, children are more likely to have serious medical problems with MIS-C than the infection itself,” he said.
The Federal Centers for Disease Control and Prevention recently approved the use of the Pfizer vaccine in adolescents younger than 12.
An FDA review of Pfizer data confirmed the results of the drugmaker’s clinical trials that the shots were safe and effective in adolescents and that the side effects were consistent with a greater age group. The trial found that 97.9% of adolescents produced enough antibodies in the month after the second dosing.
James T. Mulder covers health and higher education. Have a news tip? Contact him at (315) 470-2245 or firstname.lastname@example.org